Study of Aplastic Anaemia with Cyclosporine in Resource Poor Setting

Management of aplastic anaemia in pregnancy in a resource poor centre

Aplastic anaemia occurring in pregnancy is a rare event with life threatening challenges for both mother and child. We present a successful fetomaternal outcome despite the challenges in the management of this rare condition in a tertiary but resource poor centre. This is case of a 37 year old Nigerian woman G6P0+5managed with repeated blood transfusions from 28 weeks of gestation for bone marr...

Prospective study of rabbit antithymocyte globulin and cyclosporine for aplastic anemia from the EBMT Severe Aplastic Anaemia Working Party.

Rabbit antithymocyte globulin (rATG; thymoglobulin, Genzyme) in combination with cyclosporine, as first-line immunosuppressive therapy, was evaluated prospectively in a multicenter, European, phase 2 pilot study, in 35 patients with aplastic anemia. Results were compared with 105 age- and disease severity-matched patients from the European Blood and Marrow Transplant registry, treated with hors...

Aplastic Anaemia.

Aplastic Anaemia in Children.

A anaemia is a life threatening blood disorder that affects a large number of children each year in India. Exposure to toxic agents like benzene, radiation and viruses like hepatitis A have been implicated in its aetiology. The incidence in developing countries is far higher compared to developed countries. Investigating a child with pancytopenia is more complex than that of an adult as numerou...

Aplastic Anaemia with Microfilaria in Marrow Aspirate

Dear Editor, Filariasis is a parasitic disorder and is endemic in many parts of the world especially in the tropical countries including India. The disease presents itsel predominantly in lymphatic and cutaneous forms and caused by Wuchereria bancrofti and Brugia malayi The adult worms can be demonstrated in a variety of aspiration cytology smears. Previously rare associations have also been re...